Obvious things

• Check the OS versions
• Check the CPU architectures
• Check the versions of the app

Check the depending shared libraries

Check if the app is using the same shared libraries.

• List the paths of shared libraries that the app depends on by ldd
• Format the output by grep, tr, and cut
• Get the MD5 hash of each shared library by md5_sum

D-Bus

• Check if the D-Bus settings are the same as the working environment

GUI app only- Check the settings of the graphics libraries

• Check the graphics library the app depends on
• Run a sample command that come with the graphics library such as glxgear.

VNC environment only- xstartup file

• Check if the xstartup file is the same as the working environment